Fonctions
Directeur de recherche DR2 CNRS
Equipe
Acteurs de la pathogénèse des infections rétrovirales
Contact
email : bruno.beaumelle[at]irim.cnrs.fr
Tél : 04 34 35 94 41
Publications
1. Phosphatidylinositol (4,5)-bisphosphate-mediated pathophysiological effect of HIV-1 Tat protein. Beaumelle B, Tóth P, Malak OA, Chopard C, Loussouarn G, Vitale N. Biochimie. 2017 May 23. pii: S0300-9084(17)30125-6.
2. HIV-Tat induces a decrease in IKr and IKsvia reduction in phosphatidylinositol-(4,5)-bisphosphate availability. Es-Salah-Lamoureux Z, Jouni M, Malak OA, Belbachir N, Al Sayed ZR, Gandon-Renard M, Lamirault G, Gauthier C, Baró I, Charpentier F, Zibara K, Lemarchand P, Beaumelle B, Gaborit N, Loussouarn G. J Mol Cell Cardiol. 2016 Oct;99:1-13.
3. Detecting HIV-1 Tat in Cell Culture Supernatants by ELISA or Western Blot. Rayne F, Debaisieux S, Tu A, Chopard C, Tryoen-Toth P, Beaumelle B. Methods Mol Biol. 2016;1354:329-42.
4. Autophagy restricts HIV-1 infection. Daussy CF, Beaumelle B, Espert L. Oncotarget. 2015 Aug 28;6(25):20752-3.
5. Bee venom phospholipase A2 as a membrane-binding vector for cell surface display or internalization of soluble proteins. Babon A, Wurceldorf T, Almunia C, Pichard S, Chenal A, Buhot C, Beaumelle B, Gillet D. Toxicon. 2016 Jun 15;116:56-62.
6. Autophagy in Mycobacterium tuberculosis and HIV infections. Espert L, Beaumelle B, Vergne I. Front Cell Infect Microbiol. 2015 Jun 2;5:49.
7. HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup. Debaisieux S, Lachambre S, Gross A, Mettling C, Besteiro S, Yezid H, Henaff D, Chopard C, Mesnard JM, Beaumelle B. Nat Commun. 2015 Feb 4;6:6211.
8. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. Sagnier S, Daussy CF, Borel S, Robert-Hebmann V, Faure M, Blanchet FP, Beaumelle B, Biard-Piechaczyk M, Espert L. J Virol. 2015 Jan;89(1):615-25.
9. Preliminary characterisation of nanotubes connecting T-cells and their use by HIV-1. Lachambre S, Chopard C, Beaumelle B. Biol Cell. 2014 Nov;106(11):394-404.
10. HIV-associated cognitive disorders: tat perturbs neurosecretion. Tryoen-Tóth P, Beaumelle B, Bader MF, Vitale N. Med Sci (Paris). 2013 Dec;29(12):1069-70.
11. HIV-1 Tat protein perturbs diacylglycerol production at the plasma membrane of neurosecretory cells during exocytosis. Vitale N, Beaumelle B, Bader MF, Tryoen-Tóth P. Commun Integr Biol. 2013 Sep 1;6(5):e25145.
12. HIV-1 Tat protein inhibits neurosecretion by binding to phosphatidylinositol 4,5-bisphosphate. Tryoen-Tóth P, Chasserot-Golaz S, Tu A, Gherib P, Bader MF, Beaumelle B, Vitale N. J Cell Sci. 2013 Jan 15;126(Pt 2):454-63.
13. HIV-1 antisense transcription is preferentially activated in primary monocyte-derived cells. Laverdure S, Gross A, Arpin-André C, Clerc I, Beaumelle B, Barbeau B, Mesnard JM. J Virol. 2012 Dec;86(24):13785-9.
14. Increasing stability and toxicity of Pseudomonas exotoxin by attaching an antiproteasic Peptide. Méré J, Chopard C, Bonhoure A, Morlon-Guyot J, Beaumelle B. Biochemistry. 2011 Nov 22;50(46):10052-60.
15. The ins and outs of HIV-1 Tat. Debaisieux S, Rayne F, Yezid H, Beaumelle B. Traffic. 2012 Mar;13(3):355-63.
