Muriaux Delphine

Position

Principal Investigator – Team Leader

Team

Membrane Domains and Viral Assembly

Education

Research Habilitation Virology (Lyon University)

Ph.D. in Molecular & Cellular Biology (Paris University, Pierre and Marie Curie)

Contact

email : delphine.muriaux_at_irim.cnrs.fr

Tél : 04 34 35 94 62

Recent Publications

HIV-1 diverts actin debranching mechanisms for particle assembly and release in CD4 T lymphocytes R. Dibsy, E. Bremaud, J. Mak, C. Favard, D. Muriaux, Nat. Commun., 2023
Tetraspanin CD82 maintains HTLV-1 biofilm polarization and is required for efficient viral transmission C. Arone, S. Martial, J. Burlaud-Gaillard, M-I Thoulouze, P. Roingeard, H. Dutartre, D. Muriaux, mBio, 2023
Specific targeting and clustering of Phosphatidylserine lipids by RSV M protein is critical for virus particle production J. Swain, M. Bierre, L. Veyrié, C-A. Richard, J-F. Eleouet, D. Muriaux, M. Bajorek. J. Biol. Chem., 2023
F-actin nanostructures rearrangements and regulation are essential for SARS-CoV2 particle production in host pulmonary cells. J. Swain, P. Merida, K. Rubio, D. Bracquemond, A. Neyret, I. Aguilar-Ordoñez, S. Günther, G. Barreto, D. Muriaux, iScience, 2023
Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling. Laplantine E, Chable-Bessia C, Oudin A, Swain J, Soria A, Merida P, Gourdelier M, Mestiri S, Besseghe I, Bremaud E, Neyret A, Lyonnais S, Favard C, Benaroch P, Hubert M, Schwartz O, Guerin M, Danckaert A, Del Nery E, Muriaux D,* Weil R.*. iScience., 2023
Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles. Gourdelier M, Swain J, Arone C, Mouttou A, Bracquemond D, Merida P, Saffarian S, Lyonnais S, Favard C, Muriaux D. Sci. Rep., 2022
Extracellular vesicles containing the I-BAR protein IRSp53 are released from the cell plasma membrane in an Arp2/3 dependent manner. de Poret A, Dibsy R, Merida P, Trausch A, Inamdar K, Muriaux D. Biol. Cell, 2022
Full assembly of HIV-1 particles requires assistance of the membrane curvature factor IRSp53. K. Inamdar, F-C. Tsai, A. de Poret, R. Dibsy, J. Manzi,P. Merida, R. Muller, P. Lappalainen, P. Roingeard, J. Mak, P. Bassereau, C. Favard, D. Muriaux*. eLife, 2021
Betacoronavirus Assembly: Clues and Perspectives for Elucidating SARS-CoV-2 Particle Formation and Egress. Bracquemond D, Muriaux D., mBio
Atomic force microscopy analysis of native infectious and inactivated SARS-CoV-2 virions. S Lyonnais, M Henaut, A Neyret, P Merida, C. Cazevieille, N Gros, C Chable-Bessia, D Muriaux. Sci. Rep, 2021
HIV-1 Gag specifically restricts PI(4,5)P₂ and cholesterol mobility in living cells creating a nanodomain platform for virus assembly. C. Favard#, J Chojnacki#, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling*, D. Muriaux*, Science Adv., 2019
Monitoring HIV-1 Assembly in Living Cells: Insights from Dynamic and Single Molecule Microscopy. K Inamdar , C Floderer , C Favard * and D Muriaux*,Viruses 2019

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