Fonction
DR2 INSERM
HDR
Equipe
Enzymes bactériennes et résistance aux antibiotiques
Contact
email : konstantin.brodolin(at)irim.cnrs.fr
Tél : 04 34 35 94 69
Publications
Vishwakarma RK, Cao AM, Morichaud Z, Perumal AS, Margeat E, Brodolin K. « Single-molecule analysis reveals the mechanism of transcription activation in M. tuberculosis » Science Advances (2018) 23, 4 (doi: 10.1126/sciadv.aao5498).
Hu Y, Morichaud Z, Perumal AS, Roquet-Baneres F, Brodolin K. (2014) Mycobacterium RbpA cooperates with the stress-response σB subunit of RNA polymerase in promoter DNA unwinding. Nucleic Acids Res. 42:10399-408.
Brodolin, K. (2013) « Antibiotics targeting bacterial RNA polymerase » in Gualerzi et al. (Eds.): Antibiotics-Targets, Mechanisms and Resistance. Wiley-VCH. P 299-321.
Hu Y, Morichaud Z, Chen S, Leonetti JP, Brodolin K. (2012) Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the sigma-A-containing RNA polymerase holoenzyme. Nucleic Acids Res. 40(14):6547-57.
Zhilina E, Esyunina D, Brodolin K, Kulbachinskiy A. (2012) Structural transitions in the transcription elongation complexes of bacterial RNA polymerase during sigma-dependent pausing. Nucleic Acids Res. 40(7):3078-91.
