Fonctions
Chercheur post-doctorant
Financement ANR
Equipe
Trafic viral, restriction et immunité innée
Contact
email : jim.zoladek[at]irim.cnrs.fr
Tél : 04 34 35 94 54
Publications
ORCID 
: 0000-0003-0715-251X
– Zoladek J, Cannac M, Seite M, Davies E, Quellec J, Barthelemy J, Gorna K, Desgraupes S, Bribes I, Salinas S, Coulpier M, Arhel NJ, Palmarini M, Simonin Y, Wilson SJ, Nisole S. MITD1 is a brain-specific interferon-inducible factor that inhibits flavivirus replication. Proc Natl Acad Sci U S A. 2025 Mar 25;122(12):e2502064122.
– Zoladek J, Deymier S, Cimarelli A, Nisole S. Not all RNAs are created equal for the antiviral RNase ISG20. Trends Microbiol. 2025 Feb 18:S0966-842X(25)00030-7.
– Serrato-Pomar I, Zoladek J, Medkour H, Narpon Q, Rey-Cadilhac F, Rossi S, French S, Modahl C, Sornjai W, Miot E, Hamel Rn Medianikov O, Missé D, Nisole S, Pompon J. Multiple flaviviruses secrete a viral non-coding RNA in mosquito salivary vesicles to enhance saliva infectivity by reducing early IFN response. BioRxiv. 2025.01.21.634113.
– Zoladek J, Caval V, Paillart JC, Decroly E, Nisole S. How Usutu virus resists ISG20-mediated restriction. Med Sci. 2024, 40(12):973-975.
– Zoladek J, El Kazzi P, Caval V, Vivet-Boudou V, Cannac M, Davies EL, Rossi S, Bribes I, Rouilly L, Simonin Y, Jouvenet N, Decroly E, Paillart JC, Wilson SJ, Nisole S. A specific domain within the 3′ untranslated region of Usutu virus confers resistance to the exonuclease ISG20. Nat Commun. 2024, 15(1):8528.
– Medkour H, Pruvost L, Gong X, Vaissayre V, Boutinaud P, Revel J, Hitakarun A, Sornjai W, Zoladek J, Smith DR, Nisole S, Nolte-t Hoen E, Bertrand-Michel J, Missé D, Marti G, Pompon J. Sphingomyelins in mosquito saliva modify the host lipidome to enhance transmission of flaviviruses by promoting viral protein levels. BioRxiv. 2024.06.14.599058.
– Zoladek J and Nisole S. Mosquito-borne flaviviruses and type I interferon: catch me if you can! Front. Microbiol. 2023, 14:1257024.
– Zoladek J, Cannac M, Cartron M, Léocadie T, Wilson SJ, Nisole S. Identification de facteurs cellulaires interférant avec la réplication des virus West Nile et Usutu. Virologie. 2023, 27(3):204-205.
– Zoladek J, Afonso PV. Des peptides dérivés de claudines inhibent les infections à Flavivirus. Med Sci. 2022, 38(12):1071-1073.
– Zoladek J, Burlaud-Gaillard J, Chazal M, Desgraupes S, Jeannin P, Gessain A, Pardigon N, Hubert M, Roingeard P, Jouvenet N, Afonso PV. Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors. Microbiol Spectr. 2022, Aug 30:e0298922.
– Zoladek J, Legros V, Jeannin P, Chazal M, Pardigon N, Ceccaldi PE, Gessain A, Jouvenet N, Afonso PV. Zika Virus Requires the Expression of Claudin-7 for Optimal Replication in Human Endothelial Cells. Front Microbiol. 2021, 12:746589.
– Legros V, Jeannin P, Burlaud-Gaillard J, Chaze T, Gianetto QG, Butler-Browne G, Mouly V, Zoladek J, Afonso PV, Gonzàlez MN, Matondo M, Riederer I, Roingeard P, Gessain A, Choumet V, Ceccaldi PE. Differentiation-dependent susceptibility of human muscle cells to Zika virus infection. PLoS Negl Trop Dis. 2020, 14(8):e0008282.
– Filippone C, Legros V, Jeannin P, Choumet V, Butler-Browne G, Zoladek J, Mouly V, Gessain A, Ceccaldi PE. Arboviruses and Muscle Disorders: From Disease to Cell Biology. Viruses. 2020, 12(6):616.