Impressive work from the Team Gaudin on the effect of COVID on the brain using cerebral organoids, organotypic culture of human brain explants from individuals without COVID-19 and post-mortem brain samples from individuals with COVID-19.
Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis. Partiot E, Hirschler A, Colomb S, Lutz W, Claeys T, Delalande F, Deffieu MS, Bare Y, Roels JRE, Gorda B, Bons J, Callon D, Andreoletti L, Labrousse M, Jacobs FMJ, Rigau V, Charlot B, Martens L, Carapito C, Ganesh G, Gaudin R. Nat Microbiol. 2024 Mar 28. doi: 10.1038/s41564-024-01657-2. Epub ahead of print. PMID: 38548923.
