Fonctions
CNRS Researcher
HDR
Team
AMI – Autophagy Machinery in Infectiosn
Contact
email : lucile.espert[at]irim.cnrs.fr
Tél : 04 34 35 94 55
Selected Publications
Villares M, Espert L and Daussy CF. Peroxisomes are underappreciated organelles hijacked by viruses. Trends in Cell Biology. 2024 Dec 11:S0962-8924(24)00248-4.
Pradel B, Cantaloube G, Villares M, Deffieu MS, Robert-Hebmann V, Lucansky V, Faure M, Chazal N, Gaudin R, Espert L. LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4+ T lymphocytes. Autophagy 2024 Apr 7:1-12
Coralie F Daussy, Mathilde Galais, Baptiste Pradel, Véronique Robert-Hebmann, Sophie Sagnier, Sophie Pattingre, Martine Biard-Piechaczyk and Lucile Espert. HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death. Autophagy. 2021 Sep;17(9):2465-2474.
Daniel J. Klionsky,…. Lucile Espert,…. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th Edition). Autophagy. 2021 Feb 8;1-382.
Baptiste Pradel, Véronique Robert-Hebmann, Lucile Espert. Regulation of Innate Immune Responses by Autophagy: A Goldmine for Viruses. Frontiers in Immunology. 2020 Oct 6;11:578038.
Jamal Alfaisal, Alice Machado, Mathilde Galais, Véronique Robert-Hebmann, Laetitia Arnauné-Pelloquin, Lucile Espert*, Martine Biard-Piechaczyk*. * Co-Last authors. HIV-1 Vpr inhibits autophagy during the early steps of infection of CD4 T cells. Biol Cell. 2019 Dec;111(12):308-318
Borel S, Robert-Hebmann V, Alfaisal J, Jain A, Faure M, Espert L, Chaloin L, Paillart JC, Johansen T, Biard-Piechaczyk M. HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy. AIDS. 2015 Jan 28;29(3):275-86.
Sagnier S, Daussy CF, Borel S, Robert-Hebmann V, Faure M, Blanchet FP, Beaumelle B, Biard-Piechaczyk M, Espert L. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. J Virol. 2015 Jan;89(1):615-25.
Denizot M, Varbanov M, Espert L, Robert-Hebmann V, Sagnier S, Garcia E, Curriu M, Mamoun R, Blanco J, Biard-Piechaczyk M. HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells. Autophagy. 2008 Nov;4(8):998-1008. Epub 2008 Nov 1.
Espert L, Codogno P, Biard-Piechaczyk M. What is the role of autophagy in HIV-1 infection? Autophagy. 2008 Apr;4(3):273-5. Epub 2007 Oct 29. Review.
Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, Varbanov M, Codogno P, Biard-Piechaczyk M. Autophagy and CD4+ T lymphocyte destruction by HIV-1. Autophagy. 2007 Jan-Feb;3(1):32-4. Epub 2007 Jan 14. Review.
Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, Varbanov M, Codogno P, Biard-Piechaczyk M. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest. 2006 Aug;116(8):2161-72.