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Robert-Hebmann Véronique


Positions

Research Engineer CNRS

Prevention Assistant

Team

Players in the Pathogenesis of the Retroviral Infections

Contact

email : veronique.hebmann[at]irim.cnrs.fr

Tél : 04 34 35 94 55

 

After a BTS in biological analyses (Lycée Marie Curie, Marseille), Véronique obtained a pHD in immunology under the supervision of Christian Devaux. During her pHD, she studied the antigenic epitopes of HIV-1 p17 and p24 gag proteins. During her pHD, she moved to Montpellier where Christian Devaux set up an HIV research team within the CRBM, and obtained a TCN position at INSERM. After several years, she was recruited at the CNRS as a study engineer, then she obtained a research engineer position in 2010. For several years, she has been working on autophagy induced during HIV-1 infection of CD4+ T lymphocytes. Following the SARS-CoV2 outbreak, her work has focused on new research projects related to the autophagy interactions with this virus.

Since 2008, she is a “prevention assistant” at IRIM. She is also responsible of the "technico-scientific service" of IRIM since January 2019, and she represents the institute on the "Campus Life" committee, and participates in the working group for a greener research at IRIM.

 

Publications

Coralie F Daussy, Mathilde Galais, Baptiste Pradel, Véronique Robert-Hebmann, Sophie Sagnier, Sophie Pattingre, Martine Biard-Piechaczyk and Lucile Espert. HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death. Autophagy. 2020 Oct 19:1-10.

Baptiste Pradel, Véronique Robert-Hebmann, Lucile Espert. Regulation of Innate Immune Responses by Autophagy: A Goldmine for Viruses. Frontiers in Immunology. 2020 Oct 6;11:578038.

Jamal Alfaisal, Alice Machado, Mathilde Galais, Véronique Robert-Hebmann, Laetitia Arnauné-Pelloquin, Lucile Espert*, Martine Biard-Piechaczyk*. * Co-Last authors. HIV-1 Vpr inhibits autophagy during the early steps of infection of CD4 T cells. Biol Cell. 2019 Dec;111(12):308-318

Mathilde Galais, Baptiste Pradel, Isabelle Vergne, Véronique Robert-Hebmann, Lucile Espert, Martine Biard-Piechaczyk. LAP (LC3-associated phagocytosis): phagocytosis or autophagy? Med Sci (Paris). 2019 Aug-Sep;35(8-9):635-642.

Gómez-Mora E, Robert-Hebmann V, García E, Massanella M, Clotet B, Cabrera C, Blanco J, Biard-Piechaczyk M. Brief Report: Impaired CD4 T-Cell Response to Autophagy in Treated HIV-1-Infected Individuals. J Acquir Immune Defic Syndr. 2017 Feb 1;74(2):201-205.

Borel S, Robert-Hebmann V, Alfaisal J, Jain A, Faure M, Espert L, Chaloin L, Paillart JC, Johansen T, Biard-Piechaczyk M. HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy. AIDS. 2015 Jan 28;29(3):275-86.

Sagnier S, Daussy CF, Borel S, Robert-Hebmann V, Faure M, Blanchet FP, Beaumelle B, Biard-Piechaczyk M, Espert L. Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes. J Virol. 2015 Jan;89(1):615-25.

Espert L, Varbanov M, Robert-Hebmann V, Sagnier S, Robbins I, Sanchez F, Lafont V, Biard-Piechaczyk M. Differential role of autophagy in CD4 T cells and macrophages during X4 and R5 HIV-1 infection. PLoS One. 2009 Jun 3;4(6):e5787.

Denizot M, Varbanov M, Espert L, Robert-Hebmann V, Sagnier S, Garcia E, Curriu M, Mamoun R, Blanco J, Biard-Piechaczyk M. HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells. Autophagy. 2008 Nov;4(8):998-1008.

Molina L, Grimaldi M, Robert-Hebmann V, Espert L, Varbanov M, Devaux C, Granier C, Biard-Piechaczyk M. Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope. Proteomics. 2007 Sep;7(17):3116-30.

Hivin P, Basbous J, Raymond F, Henaff D, Arpin-André C, Robert-Hebmann V, Barbeau B, Mesnard JM. The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies. Retrovirology. 2007 Feb 16;4:14.

Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, Varbanov M, Codogno P, Biard-Piechaczyk M. Autophagy and CD4+ T lymphocyte destruction by HIV-1. Autophagy. 2007 Jan-Feb;3(1):32-4.

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IRIM
Institut de Recherche en Infectiologie de Montpellier
UMR 9004 - CNRS / UM
1919 route de Mende - 34293 Montpellier cedex 5
FRANCE

 

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