Daher Wassim


INSERM Tenure Researcher



Mycobacterial Pathogenesis and Novel Therapeutic Targets


email : wassim.daher(at)irim.cnrs.fr

Phone : +33 (0)4 34 35 94 45

Publications (last 5 years)

Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny.

Berry L, Chen CT, Francia ME, Guerin A, Graindorge A, Saliou JM, Grandmougin M, Wein S, Bechara C, Morlon-Guyot J, Bordat Y, Gubbels MJ, Lebrun M, Dubremetz JF, Daher W.

Cell Mol Life Sci. 2018 Jul 26. doi: 10.1007/s00018-018-2889-6.

Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii.

Morlon-Guyot J, Berry L, Sauquet I, Singh Pall G, El Hajj H, Meissner M, Daher W.

Mol Biochem Parasitol. 2018 Jul;223:19-30. doi: 10.1016/j.molbiopara.2018.06.003.

A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis.

Morlon-Guyot J, El Hajj H, Martin K, Fois A, Carrillo A, Berry L, Burchmore R, Meissner M, Lebrun M, Daher W.

Cell Microbiol. 2018 Jun 17:e12870. doi: 10.1111/cmi.12870.

Characterisation of two Toxoplasma PROPPINs homologous to Atg18/WIPI suggests they have evolved distinct specialised functions.

Nguyen HM, Liu S, Daher W, Tan F, Besteiro S.

PLoS One. 2018 Apr 16;13(4):e0195921. doi: 10.1371/journal.pone.0195921.

Phosphoinositides and their functions in apicomplexan parasites.

Wengelnik K, Daher W, Lebrun M.

Int J Parasitol. 2018 Jun;48(7):493-504. doi: 10.1016/j.ijpara.2018.01.009.

Towards a molecular architecture of the centrosome in Toxoplasma gondii.

Morlon-Guyot J, Francia ME, Dubremetz JF, Daher W.

Cytoskeleton (Hoboken). 2017 Feb;74(2):55-71. doi: 10.1002/cm.21353.

Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2.

Daher W, Morlon-Guyot J, Alayi TD, Tomavo S, Wengelnik K, Lebrun M.

Mol Biochem Parasitol. 2016 May;207(1):39-44. doi: 10.1016/j.molbiopara.2016.03.011.

Vacuolar protein sorting mechanisms in apicomplexan parasites.

Jimenez-Ruiz E, Morlon-Guyot J, Daher W, Meissner M.

Mol Biochem Parasitol. 2016 Sep - Oct;209(1-2):18-25. doi: 10.1016/j.molbiopara.2016.01.007.

The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence.

Berry L, Chen CT, Reininger L, Carvalho TG, El Hajj H, Morlon-Guyot J, Bordat Y, Lebrun M, Gubbels MJ, Doerig C, Daher W.

Cell Microbiol. 2016 Aug;18(8):1106-1120. doi: 10.1111/cmi.12571.

Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles.

Morlon-Guyot J, Pastore S, Berry L, Lebrun M, Daher W.

Cell Microbiol. 2015 Aug;17(8):1157-78. doi: 10.1111/cmi.12426.

Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii.

Daher W, Morlon-Guyot J, Sheiner L, Lentini G, Berry L, Tawk L, Dubremetz JF, Wengelnik K, Striepen B, Lebrun M.

Cell Microbiol. 2015 Apr;17(4):559-78. doi: 10.1111/cmi.12383. .

Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress.

Salamun J, Kallio JP, Daher W, Soldati-Favre D, Kursula I.

FASEB J. 2014 Nov;28(11):4729-47. doi: 10.1096/fj.14-252569.

The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival.

Morlon-Guyot J, Berry L, Chen CT, Gubbels MJ, Lebrun M, Daher W.

Cell Microbiol. 2014 Jan;16(1):95-114. doi: 10.1111/cmi.12186.

Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii.

Kong-Hap MA, Mouammine A, Daher W, Berry L, Lebrun M, Dubremetz JF, Besteiro S.

Autophagy. 2013 Sep;9(9):1334-48. doi: 10.4161/auto.25189.

Toxoplasma gondii myosin F, an essential motor for centrosomes positioning and apicoplast inheritance.

Jacot D, Daher W, Soldati-Favre D.

EMBO J. 2013 Jun 12;32(12):1702-16. doi: 10.1038/emboj.2013.113.








Institut de Recherche en Infectiologie de Montpellier
UMR 9004 - CNRS / UM
1919 route de Mende - 34293 Montpellier cedex 5