Trombinoscope

Goujon Caroline

Fonctions

Responsable d'équipe ATIP-Avenir

Chargée de recherche CR1 INSERM

Equipe

Interféron et restriction antivirale

Contact

email : caroline.goujon[at]irim.cnrs.fr

Tél : 04 34 35 94 33

 

Publications

 

Dicks, M., Goujon, C., Pollpeter D., Betancor G., Apolonia L., Bergeron J.R., Malim M.H. (2016) Oligomerization requirements for MX2 mediated suppression of HIV-1 infection. Journal of Virology 90 (1), 22-32. 

 

Doyle, T., Goujon, C., and Malim, M.H. (2015). HIV-1 and interferons: who's interfering with whom? Nature Reviews Microbiology 13, 403-413.

 

Goujon, C.#, Greenbury, R.A., Papaioannou, S., Doyle, T., and Malim, M.H.# (2015). A Triple-Arginine Motif in the Amino-Terminal Domain and Oligomerization Are Required for HIV-1 Inhibition by Human MX2. Journal of Virology 89, 4676-4680.

 

Goujon, C.#, Moncorge, O., Bauby, H., Doyle, T., Barclay, W.S., and Malim, M.H.# (2014). Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor. Journal of Virology 88, 9017-9026.

 

Goujon, C., Moncorge, O., Bauby, H., Doyle, T., Ward, C.C., Schaller, T., Hue, S., Barclay, W.S., Schulz, R., and Malim, M.H. (2013). Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature 502, 559-562.

 

Schaller, T., Bauby, H., Hué, S, Malim, MH, Goujon, C#. (2014) New insights into an X-traordinary viral protein. Frontiers in Microbiology. Apr 8;5:126.

 

Goujon, C.*, Schaller, T.*, Galao, R.P., Amie, S.M., Kim, B., Olivieri, K., Neil, S.J., and Malim, M.H. (2013). Evidence for IFNalpha-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology 10, 23.

 

Schaller, T., Goujon, C., and Malim, M.H. (2012). AIDS/HIV. HIV interplay with SAMHD1. Science 335, 1313-1314.

 

Koning, F.A.*, Goujon, C.*, Bauby, H.*, and Malim, M.H. (2011). Target cell-mediated editing of HIV-1 cDNA by APOBEC3 proteins in human macrophages. Journal of Virology 85, 13448-13452.

 

Berger, G., Durand, S., Goujon, C., Nguyen, X.N., Cordeil, S., Darlix, J.L., and Cimarelli, A. A simple, versatile and efficient method to genetically modify human monocyte-derived dendritic cells with HIV-1-derived lentiviral vectors (2011). Nature Protocols, 6, 806-816.

 

Goujon, C., and Malim, M.H. (2010). Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells. Journal of Virology 84, 9254-9266.

 

Berger, G., Goujon, C., Darlix, J.L., and Cimarelli, A. (2009) SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors. Gene Therapy, 16, 159-163.

 

Goujon, C., Arfi, V., Pertel, T., Luban, J., Lienard, J., Rigal, D., Darlix, J.L., and Cimarelli, A. (2008). Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells. Journal of Virology 82, 12335-12345.

 

Goujon, C., Riviere, L., Jarrosson-Wuilleme, L., Bernaud, J., Rigal, D., Darlix, J.L., and Cimarelli, A. (2007). SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology 4, 2.

 

Goujon, C., Jarrosson-Wuilleme, L., Bernaud, J., Rigal, D., Darlix, J.L., and Cimarelli, A. (2006). With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC). Gene Therapy 13, 991-994.

 

Jarrosson-Wuilleme, L., Goujon, C., Bernaud, J., Rigal, D., Darlix, J.L., and Cimarelli, A. (2006) Transduction of nondividing human macrophages with gammaretrovirus-derived vectors. Journal of Virology, 80, 1152-1159.

 

Goujon, C., Jarrosson-Wuilleme, L., Bernaud, J., Rigal, D., Darlix, J.L., and Cimarelli, A. (2003). Heterologous human immunodeficiency virus type 1 lentiviral vectors packaging a simian immunodeficiency virus-derived genome display a specific postentry transduction defect in dendritic cells. Journal of Virology 77, 9295-9304.

 

Bartosch, B., Vitelli, A., Granier, C., Goujon, C., Dubuisson, J., Pascale, S., Scarselli, E., Cortese, R., Nicosia, A., and Cosset, F.L. (2003) Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor. Journal of Biological Chemistry, 278, 41624-41630.

 

Dumonceaux, J., Goujon, C., Joliot, V., Briand, P., and Hazan, U. (2001 Determination of essential amino acids involved in the CD4-independent tropism of the X4 human immunodeficiency virus type 1 m7NDK isolate: role of potential N glycosylations in the C2 and V3 regions of gp120. Journal of Virology, 75, 5425-5428.

 

Book chapter

Goujon, C. MX2 and HIV-1 restriction. Encyclopedia of AIDS (Springer), 2015.

 

 

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IRIM
Institut de Recherche en Infectiologie de Montpellier
UMR 9004 - CNRS / UM
1919 route de Mende - 34293 Montpellier cedex 5
FRANCE

 

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