Fonctions

Directeur de recherche DR1 CNRS

Equipe

Acteurs de la pathogénèse des infections rétrovirales

Contact

email : jean-michel.mesnard[at]irim.cnrs.fr

Tél : 04 34 35 94 40

 

Publications

1. Hijacking of the AP-1 signaling pathway during development of ATL. Gazon H, Barbeau B, Mesnard JM, Péloponèse JM Jr. Front. Microbiol. 2018 Jan 15;8:2686.

2. The tenth gene of HIV. Cassan É, Arigon-Chifolleau AM, Mesnard JM, Gros A, Gascuel O. Med Sci (Paris). 2017 May;33(5):484-485.

3. Concomitant emergence of the antisense protein gene of HIV-1 and of the pandemic. Cassan E, Arigon-Chifolleau AM, Mesnard JM, Gross A, Gascuel O. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11537-11542.

4.Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients. Gazon H, Belrose G, Terol M, Meniane JC, Mesnard JM, Césaire R, Peloponese JM Jr.Oncotarget. 2016 May 24;7(21):30258-75.

5. Roles of HTLV-1 basic Zip Factor (HBZ) in Viral Chronicity and Leukemic Transformation. Potential New Therapeutic Approaches to Prevent and Treat HTLV-1-Related Diseases. Mesnard JM, Barbeau B, Césaire R, Péloponèse JM.Viruses. 2015 Dec 9;7(12):6490-505.

6. The HIV-1 antisense protein (ASP) induces CD8 T cell responses during chronic infection. Bet A, Maze EA, Bansal A, Sterrett S, Gross A, Graff-Dubois S, Samri A, Guihot A, Katlama C, Theodorou I, Mesnard JM, Moris A, Goepfert PA, Cardinaud S. Retrovirology. 2015 Feb 10;12:15.

7. Does chronic infection in retroviruses have a sense? Barbeau B, Mesnard JM. Trends Microbiol. 2015 Jun;23(6):367-75. Review.

8. HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup. Debaisieux S, Lachambre S, Gross A, Mettling C, Besteiro S, Yezid H, Henaff D, Chopard C, Mesnard JM, Beaumelle B.Nat Commun. 2015 Feb 4;6:6211.

9. Reviving an old HIV-1 gene: the HIV-1 antisense protein. Torresilla C, Mesnard JM, Barbeau B.Curr HIV Res. 2015;13(2):117-24. Review.

10. HBZ stimulates brain-derived neurotrophic factor/TrkB autocrine/paracrine signaling to promote survival of human T-cell leukemia virus type 1-Infected T cells. Polakowski N, Terol M, Hoang K, Nash I, Laverdure S, Gazon H, Belrose G, Mesnard JM, Césaire R, Péloponèse JM, Lemasson I. J Virol. 2014 Nov;88(22):13482-94.

11. Construction of a reporter vector for analysis of bidirectional transcriptional activity of retrovirus LTR. Arpin-André C, Laverdure S, Barbeau B, Gross A, Mesnard JM. Plasmid. 2014 Jul;74:45-51.

12. Human T-cell leukemia virus type 3 (HTLV-3) and HTLV-4 antisense-transcript-encoded proteins interact and transactivate Jun family-dependent transcription via their atypical bZIP motif. Larocque É, André-Arpin C, Borowiak M, Lemay G, Switzer WM, Duc Dodon M, Mesnard JM, Barbeau B. J Virol. 2014 Aug;88(16):8956-70.

13. Functional comparison of antisense proteins of HTLV-1 and HTLV-2 in viral pathogenesis. Barbeau B, Peloponese JM, Mesnard JM. Front Microbiol. 2013 Aug 7;4:226.

14. HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene. Borowiak M, Kuhlmann AS, Girard S, Gazzolo L, Mesnard JM, Jalinot P, Dodon MD. Carcinogenesis. 2013 Nov;34(11):2664-72.

15. Increased osteopontin expression in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patient cells is associated with IL-17 expression. Sarkis S, Belrose G, Peloponese JM Jr, Olindo S, Césaire R, Mesnard JM, Gross A. J Clin Virol. 2013 Sep;58(1):295-8.

16. Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy. Torresilla C, Larocque É, Landry S, Halin M, Coulombe Y, Masson JY, Mesnard JM, Barbeau B. J Virol. 2013 May;87(9):5089-105.

17. HIV-1 antisense transcription is preferentially activated in primary monocyte-derived cells. Laverdure S, Gross A, Arpin-André C, Clerc I, Beaumelle B, Barbeau B, Mesnard JM. J Virol. 2012 Dec;86(24):13785-9.

18. Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat. Gazon H, Lemasson I, Polakowski N, Césaire R, Matsuoka M, Barbeau B, Mesnard JM, Peloponese JM Jr. J Virol. 2012 Sep;86(17):9070-8.

19. Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells. Macaire H, Riquet A, Moncollin V, Biémont-Trescol MC, Duc Dodon M, Hermine O, Debaud AL, Mahieux R, Mesnard JM, Pierre M, Gazzolo L, Bonnefoy N, Valentin H. J Biol Chem. 2012 Jun 15;287(25):21357-70.

20. The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP. Wurm T, Wright DG, Polakowski N, Mesnard JM, Lemasson I. Nucleic Acids Res. 2012 Jul;40(13):5910-25.

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IRIM
Institut de Recherche en Infectiologie de Montpellier
UMR 9004 - CNRS / UM
1919 route de Mende - 34293 Montpellier cedex 5
FRANCE

 

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